Name: Denagard 80% (antibacterial veterinary drug for systemic use)
Ingredients: 1 g of the product contains the active substance: Tiamulin hydrogen fumarate – 800 mg. gelatin
Pharmaceutical form: Powder for oral administration.
Pharmacological properties: Tiamulin is a semi-synthetic antibiotic that belongs to the group of Pleuromutilin The antibiotic has a bacteriostatic effect, inhibiting the synthesis of protein in sensitive microorganisms. The product is active against gram-positive and gram-negative microorganisms (Brachyspira innocens, Brachyspira pilosicoli, Leptospira spp., Clostridium perfringens, Streptococcus spp., Staphylococcus spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Pasteurella multocida, Actinomyces pyogenes, Actinobacillus spp., Fusobacterium spp., Klebsiella pneumoniae, Haemophilus spp., Bacteroides spp., Campylobacter coli, Lawsonia intracellular is), as well as chlamydia and mycoplasmas (Mycoplasma hyopneumoniae, Mycoplasma hyosynoviae, M. hyorhinis, M. bovis, and others).
Groups of animals: Pigs:
Indications for use: Treatment of pigs suffering dysentery, colitis, ileitis, enzootic pneumonia caused by microorganisms (Brachyspira hyodysenteriae, Brachyspira pilosicoli, Lawsonia intracellularis, Mycoplasma hyopneumoniae), susceptible to tiamulin.
Contraindications: Hypersensitivity to tiamulin. Do not use products containing monensin, narazin or salinomycin in pigs for at least 7 days prior to, during and after treatment with tiamulin. This can lead to a deterioration in health or even death.
Special precautions for application: In the case of reduced feed intake, in order to achieve the therapeutic dose of the product, it is advisable to increase the levels of introduction into feed. In acute cases and in the event of serious animal disease, accompanied by reduction in feed intake, the product should be used in a suitable dosage form, such as injection or oral solution.
Use during pregnancy, lactation, laying periods: Tiamulin can be used during pregnancy and lactation.
Interaction with other products or other forms of interaction: The product is prohibited to be used simultaneously with salinomycin, monensin, narasin. The label on the packaging of the feed additive must contain information on the inability to use tiamulin with the feed containing the above products.
Dosage forms and routes of administration for animals of different age Administered orally with feed. In the calculations for obtaining the required dose and multiplicity of addition, it is necessary to apply the following formula: Number of preparation (ppm or mg / kg of feed) = dose of the preparation (mg / kg of body weight) x body weight of (kg / average daily feed intake (kg) (see more details in the product insert)
Withdrawal period: Slaughter of animals for meat is allowed 6 days after last administration of the product. Meat obtained before that period is utilized or fed to unproductive animals, depending on the conclusion of the veterinarian.
Pharmaceutical features: Forms of incompatibility: Do not use simultaneously with monensin, salinomycin, narasin
Shelf life: Shelf life of the final product: 3 years Shelf life after the first opening of the primary packaging: 12 weeks
Nature and composition of original packaging: 25 kg polyethylene barrel Special precautions for handling unused product or its residues: In accordance with local requirements for the disposal of unused medicines.